Frontman Julian Casablancas and his bandmates treated the 18,500-strong crowd to a 90 minute set of anthems from Automatic Stop to Someday.
Special guests Fontaines DC sent the crowd wild following support spots from Isle of Wight indie rock band Wet Leg and punk outfit The Lounge Society.
Take a look at our picture gallery below.
Lytham Festival continues tonight with Tears For Fears tonight and British music icon Paul Weller headlining the final night on Sunday.
In case you missed them – Simply Red and Elbow crowd pictures from earlier this week.
Plus, check out the spectacular scenes from the opening night with Diana Ross.
Take a look at our picture gallery below.