Michael Appleton will once again be without seven first-team players as he prepares to face his former club.
Sonny Carey serves the second game of his three-match suspension, while Luke Garbutt, Kevin Stewart, Charlie Patino, Lewis Fiorini, Keshi Anderson and Jake Beesley all remain sidelined.
It forced Appleton change from a 4-3-3 system to a 4-4-2 on Saturday, which made for an enthralling 3-3 draw against Bristol City.
Will Pool stick with the same side or look to mix things up?
Here’s how we think the Seasiders might line up...
1. The last dance?
Blackpool fans will be hoping tonight's game isn't the last they see of Josh Bowler in a tangerine shirt Photo: CameraSport - Dave Howarth
2. GK - Dan Grimshaw
Grimmy will be hoping for a bit of respite after back-to-back 3-3 draws. Photo: CameraSport - Dave Howarth
3. RB - Jordan Gabriel
The Seasiders will be desperate to keen Gabriel fit with Andy Lyons not arriving until January. Photo: CameraSport - Dave Howarth
4. CB - Marvin Ekpiteta
The skipper has delivered some outstanding displays in recent weeks. Photo: CameraSport - Dave Howarth
5. CB - Jordan Thorniley
With a three-game week, Thorniley could start after replacing Rhys Williams at half-time during the weekend's draw against Bristol City. Photo: CameraSport - Dave Howarth
6. LB - Dom Thompson
The summer recruit will be looking to build on Saturday's Man of the Match display. Photo: CameraSport - Dave Howarth