Jordan Rhodes claimed a hat-trick, while Kylian Kouassi marked his league debut for the club with a goal.
Here are some of the best fan photos:
1. Blackpool fans
Blackpool fans enjoyed the 4-1 victory over Reading. Photo: CameraSport - Lee Parker
2. Blackpool fans
Blackpool fans enjoyed the 4-1 victory over Reading. Photo: CameraSport - Lee Parker
3. Blackpool fans
Blackpool fans enjoyed the 4-1 victory over Reading. Photo: CameraSport - Lee Parker
4. Blackpool fans
Blackpool fans enjoyed the 4-1 victory over Reading. Photo: CameraSport - Lee Parker
5. Blackpool fans
Blackpool fans enjoyed the 4-1 victory over Reading. Photo: CameraSport - Lee Parker
6. Blackpool fans
Blackpool fans enjoyed the 4-1 victory over Reading. Photo: CameraSport - Lee Parker