The area will benefit from Operation Cleansweep, where officers from Wyre Borough Council, Lancashire Police, Lancashire Fire & Rescue, Wyre Housing Association and other agencies increase efforts to make neighbourhoods cleaner and safer.
Graffiti, fly-tipping, vandalism, litter, dog fouling and anti-social behaviour all come under the spotlight in Knott End on September 15 and 16.
Visual assessments are currently taking place to identify particular hot spots ahead of the operation itself.
Community groups are also being encouraged to get involved and report problems.
Tenants of Wyre Housing Association will be able to get rid of their household rubbish, with the exception of white goods, courtesy of skips sited on certain estates.
These skips will be manned and replaced as quickly as they are filled.
Local schools are also doing their bit by holding litter picks, while mobile police, fire and Wyre Community Safety Partnership units will park up to give advice and consult with residents in Barton Square car park.
Behind the scenes, there will be increased checks to identify TV licence dodgers, businesses not disposing of waste properly and unlicensed vehicles.
Cleansweep co-ordinator Sue Leech, Anti-social Behaviour Co-ordinator for Wyre Borough Council, said: "Similar operations in other parts of the borough have proved to be a big success, not just visually but also by bringing individual neighbourhoods together.
"We will be doing what we can to clean up the areas that need it most and we hope the results will encourage residents and visitors to respect their community in the longer term."
Sergeant Gary Tunstall, of Lancashire Police, said: "It's important that the more rural communities in Wyre benefit from this targeting of problems that are causing issues for them in their ward areas. Graffiti, vandalism and other visible crime really has a negative impact on communities and we hope to make a difference that the community can actually see for themselves."